Recognizing 100 CEOs & C-level Executives

David Greene

ceo

Location: Scottsdale, AZ

Founded: 2013

Industry: Health, Wellness & Fitness

It started with a question few dared to ask: Why weren’t more people benefiting from regenerative medicine? Dr. David Greene, chief executive officer of R3 Stem Cell, didn’t wait for the answer—he built the solution. A trained physician turned entrepreneur, Dr. Greene walked away from the traditional healthcare model to pioneer something disruptive, ethical and profoundly impactful.

Dr. Greene’s journey into regenerative medicine was unconventional. While most executives fine-tune business plans, he was charting a new clinical frontier. His vision wasn’t born from profit potential, but from a growing frustration with how limited patients’ options were. At a time when regenerative therapy remained misunderstood and underutilized, Dr. Greene saw a future where it could restore lives, relieve suffering and reduce dependency on surgery or long-term medication.

R3 Stem Cell has since become a global leader in regenerative services. Under Dr. Greene’s leadership, the company has grown consistently, poised to surpass $15 million in revenue. Yet financial milestones pale in comparison to the human impact. The organization has helped thousands of patients worldwide regain mobility, freedom and confidence—without invasive procedures. Dr. Greene’s model combined scientific rigor, patient education and a scalable provider network, making stem cell therapies more accessible and trusted than ever before.

His Titan 100 Honoree recognition underscores a leadership philosophy that refuses to follow outdated rules. Dr. Greene is redefining what innovation looks like in healthcare—not in labs alone, but in clinics, communities and conversations. He doesn’t just want people to know about regenerative therapy; he wants them to believe in it.

Internally, Dr. Greene fosters a culture of alignment. Every member of the R3 team—from clinical educators to administrators—understands their role in advancing patient-centered care. He believes innovation without communication is useless. That’s why he invests heavily in education, not just for providers, but for patients navigating a world filled with misinformation. He knows that transformation begins with trust.

Dr. Greene’s passion is unwavering. Rather than pursuing flash-in-the-pan tech, he champions therapies with the power to change how people heal. He surrounds himself with like-minded disruptors, regularly exchanging ideas and refining strategies. It’s how he sustains momentum—by staying grounded in mission and focused on outcomes.

Among his proudest accomplishments is the global expansion of R3 Stem Cell’s network. With over 45 centers in the U.S. and international clinics opening across five continents, Dr. Greene is exporting not just services, but a new standard of care. This growth has been strategic, patient-focused and uncompromising in quality. R3 Stem Cell’s global model ensures consistency in training, outcomes and ethical standards—a rare trifecta in a rapidly evolving field.

Dr. Greene isn’t just running a business; he’s stewarding a movement. His leadership proves that when science and empathy intersect, true innovation occurs. He’s not interested in short-term wins—he’s invested in generational change.

That kind of bold, principled disruption is the signature of Dr. Greene. And it’s exactly what makes him a Titan.

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